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What Is Inflammatory Osteoarthritis? Question: What is inflammatory osteoarthritis? However, each type of inflammatory arthritis can also have unique symptoms or impact a specific area of the body. RA most often impacts the small joints of the body, such as those in the hands, feet , and wrists. Typically, more than one joint is affected.
Additionally, more often than not, the same joints on both sides of the body are involved. This is called symmetric arthritis. Other symptoms of RA include:. In some instances, RA symptoms can get worse over a period of time.
This is often referred to as a flare. PsA can affect a variety of different joints in the body. In fact, there are several types of PsA , which are classified by their severity and the area of the body that they affect. Additional symptoms of PsA include:. As in RA, people with PsA can also experience flares. There are many things that can bring on a PsA flare. The main symptoms of axial spondyloarthritis are chronic lower back pain and inflammation of the SI joints.
This can lead to:. Those with axial spondyloarthritis typically have two or more other disease features, which can include :. Lupus can impact many organs and tissues. In addition to joint pain and inflammation, a person with lupus may experience:. There are several types of JIA and specific symptoms can vary. In addition to general symptoms of inflammatory arthritis, an individual with JIA can also have:.
Gout is characterized by sudden, painful joint swelling. During this time, the affected joint becomes very sensitive and even the slightest bit of pressure can cause serious pain. The joint may also appear red and feel warm. Initially, gout affects only one joint, which is typically the big toe. RA is an autoimmune condition. In the case of RA, the immune system attacks the synovium, which is the lining around the joint that facilitates smooth joint movement.
The exact cause of RA still remains a mystery. Those assigned female at birth are more likely to develop RA than those assigned male at birth.
The condition typically develops in middle age. PsA is also an autoimmune condition. PsA is estimated to affect between 20 and 30 percent of people with psoriasis. A systematic review published in May stated, "Human osteoarthritis is a systemic musculoskeletal disorder involving activation of innate and adaptive immune systems accompanied by inflammation exemplified by the elevated production of proinflammatory cytokines , which play a significant role in the progression of the disease.
Osteoarthritis , also known as degenerative joint disease, is caused by the breakdown of articular cartilage—the type of cartilage that covers the ends of bones in a joint. Over time, most older adults will develop some form of painful osteoarthritis in a joint or in more than one joint, such as the knees, hips, spine, or hand. While pain is common in OA, obvious inflammation — redness and swelling — is usually considered a primary symptom with other types of arthritis.
However, as osteoarthritis progresses, inflammation can occur around an affected joint. It was thought that the inflammation is caused by cartilage fragments that break off and irritate the synovium the smooth lining of a joint. However, MRIs taken during the early stages of osteoarthritis sometimes detect synovitis inflammation even though the joint cartilage still appears normal. This indicates that other joint structures also may be involved in triggering inflammation.
Before synovitis is evident or joint degeneration is seen, the levels of markers of inflammation increase in the blood and the joint fluid. These inflammatory cytokines include C-reactive protein CRP and interleukin-6 in synovial fluid. The case is strong that there is inflammation occurring earlier in osteoarthritis and this may be the cause of the progression of symptoms. There have been recent studies of inflammation in spinal arthritis that pointed to the entheses the sites where ligaments or tendons attach to bone as a potential location of joint inflammation in OA.
It looks like the question is similar to which came first, the chicken or the egg? Is mechanical damage due to overuse or a trauma what leads to low-grade chronic inflammation, causing the loss of cartilage that results in a further loss, more inflammation, synovitis, and degeneration? More research is looking into these questions.
The answers may lead to better drugs that will break the cycle of inflammation and stop the progression of damage to the joint. Psoriatic arthritis can present with different patterns of joint involvement, often with asymmetric joint involvement. Psoriatic arthritis can also cause inflammatory back pain. Some of the treatments used to treat psoriatic arthritis can also help with psoriasis. Psoriatic arthritis patients benefit from rheumatology care. Back pain is a common complaint in the general population.
Patients with ankylosing spondylitis and axial spondyloarthritis present with inflammatory back pain. Inflammatory back pain usually starts before age Inflammatory back pain causes chronic back pain and does not start abruptly as with injury.
Inflammatory back pain patients benefit from rheumatology care. Schedule an appointment with your primary care provider to discuss a referral to Dr. Rheumatology with Dr.
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